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RSV Dipstick and Cassette
RSV Dipstick and Cassette is a rapid, qualitative, chromatographic immunoassay which detects RSV in NPS sample.
The RSV test is intended for the rapid, qualitative detection of respiratory syncytial virus (RSV) directly from nasopharyngeal swab, and nasal aspirate specimens in children less than 6 years and adults over the age of 60. RSV is the major cause of serious lower respiratory disease, including bronchiolitis and pneumonia.

RSV, Respiratory Syncytial Virus, is the major cause of respiratory illness in all ages. It represents the most frequent cause of serious respiratory tract infections in infants and children younger than 4 years of age but is also responsible for severe problems in elderly and immunocompromised patients giving rise to high death rates. Pneumonia and bronchiolitis are the two most frequent severe infections prevalent in infants aged 2 to 6 months. Infection of older children and adult may be mild, usually self-limiting, causing nasal stuffiness and discharge not distinguishable from a common cold.

Each year, up to 50 % of infants are infected. RSV 125,000 hospitalisations in the US. Those children who require hospitalisation are newborns and those who suffer from asthma, lung disorders or heart problems. Moreover, RSV bronchiolitis in the first year of life is one of the most important risk factors for the subsequent development of asthma.

It is a highly contagious disease through contact with respiratory secretions. It is also a common cause of nosocomial infections whose prevalence increases during community outbreaks through casual contacts. RSV affects both the upper and lower respiratory tracts, but pneumonia and bronchiolitis are the most prevalent lower respiratory illnesses. Bronchiolitis could be recognized by cough,wheeze, onset of dyspnea, increase of respiratory rate up to 40 breaths per minute and bluish discoloration of the skin around the mouth. Findings of crackles and respiratory distress are common symptoms of pneumonia.

The RSV test is a dipstick immunoassay that allows the capture and visual detection of RSV antigen (viral fusion protein). The patient specimen is placed in the extractin buffer, enhancing the exposure of the viral fusion protein antigen. After extraction, the Test Strip is placed in the extraction buffer where the RSV fusion proteins in the specimen will react with the reagents in the Test Strip.
This dipstick can detect RSV either in nasopharyngeal secretions or in culture supernatant after several days in order to reach a better sensitivity. When the strip is dipped into the extraction solution of NPS (nasopharyngeal secretions) or culture extracted solution, the solubilized conjugate migrates with the sample by passive diffusion and both the conjugate and sample material come into contact with the anti-RSV antibody that it is adsorbed onto the nitrocellulose strip. If the sample contains RSV, the conjugate-RSV complex will remain bound to the anti-RSV antibody adsorbed onto the nitrocellulose. The result is visible within 15 minutes in the form of a red line that develops on the strip. The solution continues to migrate to encounter a control reagent that binds a control conjugate, thereby producing a second red line.

High performance:
--High Sensitivity: 93%

--High Specificity: 96%

--Ease-to-use

--Reliable results

--Clear backgroud, longer shelf life


Ordering information:
Product Code Product Description Specimen Package Size
AN2003C RSV Cassette NPS 25tests/kit
AN203S RSV  Dipstick NPS 25tests/kit